Lactobacillus plantarum 10 log CFU daily 4-weeks alleviated stress and anxiety while enhancing memory and cognition in stressed adults (Clinical Nutrition10 September 2018)
L. casei may be an ideal probiotics for the prevention and treatment of denture-related stomatitis (Archives of Oral Biology 76 (2017 1 – 6)
Lactobacillus plantarum supplementation 10B cfu/day for 12 weeks reduced SCORAD in children with atopic dermatitis (Beneficial Microbes, 2017;8(5): 833-840)
Lactobacillus casei was identified the best for H. pylori eradication rates in children, Lactobacillus acidophilus and Lactobacillus rhamnosus for total side effects (Eur J Clin Pharmacol 14 June 2017)
L acidophilus and Bifidobacterium sp. could safely and effectively decrease lactose intolerance symptoms and hydrogen breath test (HBT ) Food Sci Nutr. 2021;9:1704–1711
L. casei contributed to weight loss while also improving the lipid metabolism in obese children Beneficial Microbes 8(4)
Lactobacillus acidophilus and Bifidobacterium longum reduced the duration of rotavirus diarrhea in young Korean children Nutrients 2017, 9, 887
Lactobacillus plantarum has Beneficial Effects on High-Intensity, Exercise-Induced Oxidative Stress, Inflammation, and Performance in Triathletes, and may be a potential ergogenic aid for better training management, physiological adaptations to exercise, and health promotion. Nutrients 2019, 11, 353
30B CFU Lactobacillus plantarum , a reported psychobiotic, can ameliorate some autism symptoms, primarily those associated with disruptive and rule breaking behaviors and hyperactivity/impulsivity, may be beneficial for children with Autism Spectrum Disorder (ASD). Nutrients 2019, 11, 820
Both L. acidophilus and B. animalis subsp. lactis, especially their combination, may exert a potent anti-inflammatory effect through modulating TLR2-mediated NF-κB and MAPK signaling pathways in inflammatory intestinal epithelial cells IECs, may be novel adjuvants for Inflammatory bowel disease (IBD) therapy Nutrients 2019, 11, 969
Lactobacillus casei 0.4 B CFUs/day for 7 days : Effective for Managing Childhood Diarrhea by Altering Gut Microbiota and Attenuating Fecal Inflammatory Markers Nutrients 2019, 11, 1150 10B CFU/day of L. plantarum and L. paracasei 8700:2 for 6 months may modulate the peripheral immune response in children with Celiac Disease Autoimmunity (CDA) Nutrients 2019, 11, 1925
Lactobacillus acidophilus 10B CFU/day over six weeks improved abdominal pain and symptom severity scores with a corresponding normalization of bowel habits in adults with Irritable Bowel Syndrome (IBS). Nutrients 2020, 12, 363
Lactobacillus Plantarum decreases kynurenine concentration and improves cognitive functions in patients with major depression. Augmentation of selective serotonin reuptake inhibitors (SSRI) treatment with 10 B CFU of Lactobacillus Plantarum twice daily for 8 weeks improved cognitive performance and decreased KYN concentration in Major Depressive disorder (MDD) patients. Psychoneuroendocrinology 100 (2019) 213–222
Lactobacillus acidophilus may reduce mycotoxin contamination Toxins 2021, 13, 185 Concerning allergic rhinitis (AR), synthesis of available data provided significant evidence of beneficial clinical and immunologic effects of probiotics in the treatment of AR, especially with seasonal AR and in particular with Lactobacillus paracasei, as demonstrated by 2016 meta-analysis by Guvenc, Am J Rhinol Allergy 2016 (GUT MICROBES 543)
2 meta-analyses (PLoS One 2015; 10, AnnMed 2015; 47:430-40) agree that there is a greater efficacy of Lactobacillus acidophilus than the other species in the reduction of total and LDL cholesterol (GUT MICROBES 543)
Research supports the hypothesis that B. lactis has a beneficial role in maintaining intestinal barrier function during gastrointestinal infections by competing and excluding potential pathogens via different mechanisms; regulating host immune defense toward pathogens in human studies, leading to reduced incidence of diarrhea, supports normal physiological function in immunosenescent elderly and competes and excludes potential pathogens, reduced intestinal transit time and increased bowel movement frequency in functional constipation, potentially by modulating gut–brain–microbiota axis, mainly via serotonin signaling pathway, through short chain fatty acids derived from microbial fermentation. B. lactis HN019TM is thus a probiotic that can contribute to relieving gut dysmotility related disorders. (Frontiers in Nutrition | www.frontiersin.org 1 December 2021 | Volume 8 | Article 790561)
Bifidobacterium lactis has significant beneficial effects on weight management and metabolic health, impact on gut mucosa and sub-mucosa (epithelial barrier function), as well as the gut immune system (Microorganisms 2021, 9, 836)
B lactis: anti-inflammation, reducing fat accumulation, inhibits the pathogen growth to promote bone health, regulating immune by increasing the levels of total IgA and antiβ-lactoglobulin IgA (Frontiers in Bioengineering and Biotechnology Dec 2021